Cord blood stem cells aim to repair hearts after attack

NCT ID NCT07134712

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new treatment called MiSaver, made from umbilical cord blood cells, for people who recently had a heart attack. The goal is to see if it safely helps the heart pump better and reduces future heart problems. About 102 participants will either receive the cell treatment or standard care, and their heart function will be tracked for a year.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 102 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥ 45 years, BMI ≤ 32 2. Patients diagnosed with acute myocardial infarction by a cardiologist, within 36 hours to 7 days post-diagnosis, and able to complete cell infusion within this period. 3. Left ventricular ejection fraction (LVEF) ≤ 45%, hemodynamically stable patients who do not require vasopressor support within 24 hours. 4. Patients with a history of coronary artery disease, who have previously undergone percutaneous coronary intervention or coronary artery bypass graft surgery, may also be included upon evaluation by a cardiologist. 5. Patients deemed unsuitable for percutaneous coronary intervention or coronary artery bypass graft surgery by a cardiologist. 6. Must agree to sign the informed consent form. 7. Subjects must use effective contraception during the study observation period and for 6 months after its conclusion to ensure no pregnancy occurs during the study. (Primarily for women of childbearing potential). 8. Agree to and comply with the required outpatient visits and examinations during the study observation period. Exclusion Criteria: 1. Age \< 45 years, BMI \> 32. 2. Women who are planning to become pregnant, are pregnant, or are breastfeeding 3. Immunodeficiency diseases caused by infection , such as Human Immunodeficiency Virus (HIV). 4. Patients diagnosed as needing coronary artery bypass surgery or potentially requiring coronary revascularization surgery within the next 6 months. 5. Severe aortic or mitral valve stenosis. 6. Life-threatening arrhythmias. 7. Malignant tumors, including all categories and cancer conditions. 8. Hematologic disorders or other severe organ diseases with an expected survival of less than one year. 9. Chronic kidney disease (eGFR \< 30 mL/min/1.73m²) or patients undergoing dialysis. 10. Patients with autoimmune diseases or those who have already received immunotherapy. 11. Patients who have undergone tumor treatment or require immunosuppressive therapy within the last three years. 12. History of transfusion reactions. 13. Recipients of bone marrow or organ transplants. 14. Liver dysfunction (bilirubin \> 2.5 mg/dL or transaminases \> 5x the upper limit of normal). 15. Patients who have previously received growth factors, cytokines, gene therapy, or stem cell therapy. 16. Subjects participating in more than one clinical trial. 17. Inability to sign the consent form or comply with outpatient follow-up after infusion therapy. 18. Patients with a known allergy to this product or its excipients (e.g., dimethyl sulfoxide, cell preservation solution).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    4 sites in 2 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Chung Shan Medical University Hospital Daqing Branch

    Taichung, Taiwan

  • Flinders Medical Centre

    Bedford Park, South Australia, 5042, Australia

    Contact Email: •••••@•••••

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    Kaohsiung City, Taiwan

  • Mackay Memorial Hospital Hsinchu Branch

    Hsinchu, Taiwan

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