Scientists hunt for hidden switches that make brittle bones worse or milder
NCT ID NCT04009733
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 23 times
Summary
This study looked at 66 adults to find small molecules called microRNAs in the blood that might explain why some people with osteogenesis imperfecta (brittle bone disease) have a mild form while others have a severe form. Researchers compared people with type 1 (mild) and type 3 (severe) OI to healthy controls. The goal was to identify which microRNAs are linked to disease severity, which could lead to better understanding of the condition.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Hôpital Edouard Herriot
Lyon, 69003, France
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