Which drug works better after infant valve surgery? new study compares mirabegron and oxybutynin
NCT ID NCT07668232
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This study looked at two drugs, mirabegron and oxybutynin, in 52 children over age 3 who had surgery for posterior urethral valves. The goal was to see which drug better improves bladder and kidney function and reduces urinary tract infections. Researchers also checked safety by monitoring blood pressure and heart rate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Mirabegron and oxybutynin
What this could lead to
If successful, this could show that mirabegron is a safer or more effective option than oxybutynin for managing bladder function after valve surgery in children.
What could go wrong
This is a small, completed trial with only 52 participants, so results may not apply to all children. The study compares two existing drugs, so no major breakthrough is expected.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
Contacts and locations
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Locations
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Qina University hospital, South Valley University Hospital
Qina, South Valley, Egypt