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Blood markers may predict heart risk after surgery

NCT ID NCT03436238

Knowledge-focused Sponsor: Linkoeping University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed over 1,200 adults having major abdominal surgery to find blood markers that could predict serious heart problems or death within 30 days and one year after surgery. Researchers measured heart injury and other factors to improve risk prediction. The goal is to help doctors identify high-risk patients earlier and potentially prevent complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,269 people

The number who actually took part.

Started

May 2017

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled for elective, major abdominal surgery at participating centres, requiring general anaesthesia, and requiring at least one overnight stay.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients undergoing elective, major abdominal surgery\*. (\*Major abdominal surgery requiring general anaesthesia, and requiring at least one overnight stay. Major abdominal surgery is defined as those classified as major OR major/complex by the Surgical Outcome Risk Tool (SORT) (www.sortsurgery.com). In essence major surgery is one that penetrates and exposes a body cavity or produces a substantial impairment of physical or physiologic function or involves extensive dissection or transection. Examples of a major abdominal surgery include, but are not limited to, any procedure involving a laparotomy or laparoscopic procedures of the stomach, duodenum, small and large intestine and rectum. It also includes but is not limited to procedures on the reproductive system (total abdominal hysterectomy, salpingo-oophorectomy) and genitourinary system (nephrectomy, cystectomy).) Exclusion Criteria: * Patient not fulfilling inclusion study criteria above and/or clinician refusal and/or non-eligible as defined below. Patients undergoing the following surgical procedures will NOT be eligible: * transplantation * trauma * endocrine * vascular * endovascular The presence of any one of the following will also lead to exclusion of the patient: * ACS at presentation (clinical assessment or documentation) * New or decompensated congestive heart failure at presentation (clinical assessment or documentation) * Documented severe aortic stenosis (valve area \< 1cm2) * Reduced LVEF (\<40%); if no LVEF is available, it will be assumed to be \>40% * Inability to follow the procedures of the study, e.g. due to language problems, dementia, etc. of the participant

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Conditions

The condition(s) this trial relates to.

Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Perioperative/postoperative complications Risk factor, cardiovascular

Contacts and locations

Locations

  • Department of Anaesthesia and Intensive Care, Linkoeping University Hospital, Region Östergötland

    Linköping, Östergötland County, 50185, Sweden

  • Eskilstuna Hospital

    Eskilstuna, Sweden

  • Kristianstad KRYH Hospital

    Kristianstad, Skåne County, Sweden

  • Ryhov County Hospital

    Jönköping, Sweden

  • Skane University Hospital Lund

    Lund, Sweden

  • Skane University Hospital Malmö

    Malmö, Sweden

  • Vrinnevi Hospital

    Norrköping, Sweden

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