New drug combo shows promise for stubborn stomach bug, but side effects common

NCT ID NCT06561711

First seen Mar 30, 2026 · Last updated May 25, 2026 · Updated 11 times

Summary

This study tested a 14-day treatment with minocycline and metronidazole for people whose H. pylori infection did not clear with previous treatments. The new combination worked as well as the standard therapy, but over half of participants had side effects. The goal was to find a better-tolerated option for this common stomach infection.

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Contacts and locations

Locations

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100191, China

  • Renji Hospital, School of Medicine, Shanghai Jiao Tong University

    Shanghai, Shanghai Municipality, 200127, China

  • Songjiang Hospital, School of Medicine, Shanghai Jiao Tong University

    Shanghai, Shanghai Municipality, China

  • The Second Affiliated Hospital of Zhejiang University school of Medicine

    Hangzhou, Zhejiang, China

Conditions

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