Can a mindfulness app supercharge brain stimulation for depression?

NCT ID NCT07369557

Recruiting now Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether adding brief guided mindfulness exercises (via a smartphone app) between sessions of accelerated brain stimulation (aiTBS) is feasible and acceptable for people with major depression. Twenty adults already receiving aiTBS as standard care will practice mindfulness for 5-15 minutes at a time over five treatment days. Researchers will track adherence, side effects, and changes in mood and mindfulness up to 12 weeks later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: guided mindfulness practice via smartphone app
What this could lead to: If successful, this could point toward a way to boost the antidepressant effects of brain stimulation by adding brief mindfulness exercises.
What could go wrong: This is a very small, early pilot study (20 people) with no control group, so results may not be generalizable. Meditation-related side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEPRESSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION

Contacts and locations

Locations

IOP
RECRUITING

Charleston, South Carolina, 29407, United States
Medical University of South Carolina (MUSC), Brain Stimulation Laboratory Institute of Psychiatry
NOT_YET_RECRUITING

Charleston, South Carolina, 29407, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.