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Milk's hidden trail: can a glass of milk reveal gut bacteria in the blood?

NCT ID NCT06944002

Knowledge-focused Sponsor: Erasmus Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

Researchers at Erasmus Medical Center are testing whether drinking milk can make bacteria from the gut appear in the blood. Healthy volunteers will avoid dairy for ten days, then drink 700 ml of milk daily for a week. The team will compare bacterial DNA in blood and stool samples to see if the blood microbiome mirrors the gut microbiome. This study could help develop a simpler way to monitor gut health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Milk product (dietary supplement)
What this could lead to
If it works, this could show that blood samples can reflect gut bacteria, offering a less invasive way to study the gut microbiome.
What could go wrong
This is a small, early study with only 9 participants, so the results may not apply broadly. The detection of bacterial DNA in blood could be inconsistent or hard to interpret.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

9 people

The number who actually took part.

Started

Jul 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years * 18.5 =\< BMI \< 25 kg/m2 * All genders included * Not be lactose intolerant * Willing to consume milk Exclusion Criteria: * Regularly used medications such as antibiotics, steroids, beta blockers, and adrenergic- stimulating agents (self-report) * Regular use of prebiotic and/or probiotics apart from yogurt and young soft cheese (self-report) * Antibiotic intake in the previous months (self-report) * Daily consumption of more than 10 cigarettes (self-report) * Chronic diseases including type 2 diabetes, hypertension, fatty liver disease, cancer, or autoimmune disease (self-report) * Internal diseases, including those of the gastrointestinal tract, lung, heart, vasculature, liver, and kidney (self-report) * Eating disorder or unconventional eating habits (self-report) * Participation in another study (self-report) * Women: pregnancy and breastfeeding (self-report)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • Erasmus MC - Department of Gastroenterology and Hepatology

    Rotterdam, 3015 GD, Netherlands

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