Cooler or warmer? new trial tests best temperature for aortic surgery safety
NCT ID NCT02860364
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether cooling patients to 32°C (mild) or 26°C (moderate) during aortic arch surgery better protects the brain and kidneys. 282 adults having planned aortic hemiarch surgery will be randomly assigned to one temperature. The goal is to see which temperature reduces complications like stroke and kidney injury.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hypothermia (mild or moderate) during surgery
What this could lead to
If mild hypothermia works better, it could reduce brain and kidney damage after aortic surgery, leading to safer procedures and faster recovery.
What could go wrong
This is a mid-stage trial with 282 patients, so results may not apply to all. The difference between mild and moderate cooling might be small, and there are always risks from major surgery itself.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for THORACIC AORTIC DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Dalhousie university
NOT_YET_RECRUITINGHalifax, Nova Scotia, B3H 3A7, Canada
Contact
-
Fraser Health Authority
RECRUITINGSurrey, British Columbia, V3T 0H1, Canada
Contact
-
Institut universitaire de cardiologie et de pneumologie de Québec
RECRUITINGQuébec, Quebec, G1V 4G5, Canada
Contact
-
Kelowna General Hospital
RECRUITINGKelowna, British Columbia, V1Y 1T2, Canada
Contact
-
London Health Sciences Centre
RECRUITINGLondon, Ontario, N6A 5A5, Canada
Contact
-
Massachusetts General
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
-
Montreal Heart Institute
RECRUITINGMontreal, Quebec, H1T 1C8, Canada
Contact
-
Ohio State University Medical Center
RECRUITINGColumbus, Ohio, 43210, United States
Contact
-
The Valley Hospital
RECRUITINGRidgewood, New Jersey, 07450, United States
Contact
Contact
-
University Health Network
RECRUITINGToronto, Ontario, M5G 2N2, Canada
Contact
-
University of British Columbia
NOT_YET_RECRUITINGVancouver, British Columbia, V6Z 1Y6, Canada
Contact
-
University of Ottawa Heart Institute
RECRUITINGOttawa, Ontario, K1Y 4W7, Canada
Contact