Head-to-Head: which migraine pill works best?

NCT ID NCT06972056

Summary

This study aims to find out which of three oral medications works best to prevent migraine attacks in adults. Researchers will compare a newer drug, atogepant, against two older, commonly used drugs, topiramate and propranolol. About 1,335 participants will be randomly assigned to take one of the three pills for 12 weeks and track their headaches in a diary to see which medicine is most effective and easiest to tolerate.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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Locations

  • Advanced Research Institute

    RECRUITING

    Portland, Oregon, 97223, United States

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  • Advanced Research Institute Ogden

    RECRUITING

    Ogden, Utah, 84405, United States

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  • Advanced Research Institute Reno

    RECRUITING

    Reno, Nevada, 89511, United States

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  • Apple Med Research

    RECRUITING

    Miami, Florida, 33126, United States

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  • Clinical Research Institute

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    Los Angeles, California, 90048, United States

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  • JFK Neuroscience Institute

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    Edison, New Jersey, 08820, United States

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  • Mayo Clinic

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    Rochester, Minnesota, 55905, United States

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  • Mayo Clinic Arizona

    RECRUITING

    Phoenix, Arizona, 85054, United States

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  • Mayo Clinic Florida

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    Jacksonville, Florida, 32066, United States

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  • Northern Arizona Healthcare

    RECRUITING

    Flagstaff, Arizona, 86001, United States

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  • Ohio State University Wexner Medical Center

    NOT_YET_RECRUITING

    Columbus, Ohio, 43210, United States

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  • USC Keck

    NOT_YET_RECRUITING

    Los Angeles, California, 90033, United States

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

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  • University of Pennsylvania

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    Philadelphia, Pennsylvania, 19107, United States

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  • Vanderbilt Medical Center

    RECRUITING

    Nashville, Tennessee, 37215, United States

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  • Wake Forest University Health

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

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  • Washington University St Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

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  • West Virginia University

    RECRUITING

    Morgantown, West Virginia, 26506, United States

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Conditions

Explore the condition pages connected to this study.