Race against time: drug trial for babies with devastating genetic disease

NCT ID NCT03822013

First seen Nov 01, 2025 · Last updated Apr 21, 2026 · Updated 22 times

Summary

This study tested whether a drug called miglustat could help control symptoms in infants with Sandhoff or Tay-Sachs disease—rare, fatal genetic conditions. The trial involved 30 infants and measured changes in symptoms like seizures, feeding problems, and hospital visits. The goal was to see if the drug could improve quality of life by reducing disease complications, not to cure the underlying condition.

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Contacts and locations

Locations

  • Kashan University Of Medical Sciences

    Kashan, Isfahan, Iran

  • Mashhad University Of Medical Sciences

    Mashhad, Khorasan, Iran

  • Tehran University Of Medical Sciences

    Tehran, Tehran Province, Iran

Conditions

Explore the condition pages connected to this study.