New Heart-Lung machine could cut surgery risks in half

NCT ID NCT05487612

First seen Apr 03, 2026 · Last updated Apr 25, 2026 · Updated 6 times

Summary

This study tests if a newer, less invasive heart-lung machine (MiECC) causes fewer serious problems after heart surgery than the standard machine. About 1300 adults having planned coronary bypass or aortic valve replacement will be randomly assigned to one of the two machines. The goal is to see if MiECC reduces complications like heart attack, stroke, kidney injury, or the need for a blood transfusion.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cardiothoracic Department AHEPA University Hospital

    RECRUITING

    Thessaloniki, 54636, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Deparment of Cardiac Surgery, Castle Hill Hospital

    ACTIVE_NOT_RECRUITING

    Hull, HU16 5JQ, United Kingdom

  • Department of Cardiac Surgery

    ACTIVE_NOT_RECRUITING

    Coswig, 06869, Germany

  • Department of Cardiac Surgery GVM Anthea Hospital

    RECRUITING

    Bari, 70124, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Cardiac Surgery GVM Maria Eleonora Hospital

    ACTIVE_NOT_RECRUITING

    Palermo, 90135, Italy

  • Department of Cardiac Surgery, Royal Papworth Hospital

    ACTIVE_NOT_RECRUITING

    Cambridge, CB2 0AY, United Kingdom

  • Department of Cardiothoracic Surgery, Hammersmith Hospital

    ACTIVE_NOT_RECRUITING

    London, W120HS, United Kingdom

  • Department of Cardiothoracic and Vascular Surgery, Ulm University Hospital

    COMPLETED

    Ulm, 89081, Germany

  • Department of Cardiovascular Surgery, Ankara City Hospital

    ACTIVE_NOT_RECRUITING

    Ankara, Turkey (Türkiye)

  • Department of Cardiovascular Surgery, Faculty of Medicine, Recep Tayyip Erdoğan University

    RECRUITING

    Rize, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Cardiovascular Surgery, Izmir Bakırçay University, Faculty of Medicine

    RECRUITING

    Izmir, Turkey (Türkiye)

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Department of Thoracic and Cardiovascular Surgery, University Medical Centre Goettingen

    ACTIVE_NOT_RECRUITING

    Göttingen, Germany

  • Perfusion Services University Health Network, Toronto General Hospital

    RECRUITING

    Toronto, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.