Could heat zap fibroids without surgery?
NCT ID NCT07780019
First seen Aug 21, 2026 ยท Last updated Aug 21, 2026
Summary
This study looks at whether a procedure called microwave ablation can safely and effectively treat symptomatic uterine fibroids in 100 premenopausal women. The procedure uses ultrasound guidance to deliver heat directly to the fibroids, aiming to shrink them and reduce symptoms like heavy bleeding and pain. Researchers will measure changes in symptom severity and quality of life using a validated questionnaire, and also assess how well the technique works across different fibroid types, sizes, and locations.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- microwave ablation
- What this could lead to
- If successful, this could offer a minimally invasive alternative to surgery for treating symptomatic uterine fibroids, potentially easing pain and heavy bleeding while preserving the uterus.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less definitive. The procedure carries risks like bleeding or injury, and its effectiveness may vary depending on fibroid type, size, and location.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2026
- Expected to finish
-
Dec 2034
An estimate. End dates often move.
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
patients undergoing mwa for symptomatic uterine fibroids will be recruited for this study
- Ages
-
18 to 56 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * symptomatic fibroids * premenopausal status * acceptable risks for general anestesia or sedation * willing to undergo mwa treatment and participate in the study Exclusion Criteria: * postmenopausal status * bleeding disorder with increased risk of bleeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Turku University Hospital
Turku, Finland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New heat therapy could free women from fibroid surgery