Can a One-Two punch shrink fibroids better?
NCT ID NCT07754877
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial tests whether adding a chemical injection to microwave ablation improves treatment for uterine fibroids, common non-cancerous tumors that can cause heavy bleeding and pain. Microwave ablation uses heat to destroy fibroid tissue, but blood flow can cool the area and reduce its effectiveness. The study compares the standard microwave ablation alone versus microwave ablation combined with a chemical agent that may block blood flow and enhance the heat effect. Researchers will measure how much the fibroids shrink, symptom improvement, and safety in 248 women.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Microwave ablation combined with lauromacrogol (chemical ablation) versus microwave ablation alone
- What this could lead to
- If the combined approach works, it could offer a more effective, less invasive treatment for uterine fibroids, potentially reducing symptoms and preserving fertility better than current options.
- What could go wrong
- This is a relatively early-stage trial, and the combination may not improve outcomes enough to justify added risks. The heat-sink effect and individual fibroid characteristics could limit the benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Aerospace center hospital
Beijing, China
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