Wrinkle-Free wonder? small study tests microtox for skin smoothness

NCT ID NCT06604832

Completed Symptom relief Sponsor: Kalpna Kay Durairaj, MD, FACS Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 1 trial tested whether injecting a botulinum toxin (prabotulinumtoxinA-xvfs, also known as Jeuveau) into the forehead can improve facial skin quality, fine wrinkles, and texture. Twenty women with mild to moderate wrinkles received the treatment on one side of their face and either a placebo or a different toxin on the other side. Doctors rated skin changes using a scientific scale and an aesthetic improvement scale over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PrabotulinumtoxinA-xvfs (Jeuveau)
What this could lead to: If it works, this could point toward a cosmetic treatment for fine wrinkles and skin texture improvement.
What could go wrong: This is a very small, early-phase trial with only 20 participants, so results may not apply to everyone. The study is also completed, so no further development is planned.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SKIN AGING SKIN WRINKLING

Contacts and locations

Locations

K. Kay Durairaj, MD, A Medical Corp.

Pasadena, California, 91105, United States

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