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Can adding a chemical peel to microneedling erase acne scars better?

NCT ID NCT07797517

Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial tests whether combining microneedling with a chemical peel improves atrophic acne scars more than microneedling alone. Sixty adults with these scars are randomly assigned to receive microneedling followed by a 35% glycolic acid peel, microneedling followed by a 15% trichloroacetic acid peel, or microneedling only. Treatments happen every two weeks. Researchers measure scar severity, participant satisfaction, pain, recovery time, and side effects to see if either combination offers extra benefit.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Microneedling with or without a chemical peel (35% glycolic acid or 15% trichloroacetic acid)
What this could lead to
If adding a chemical peel to microneedling improves scar appearance more than microneedling alone, it could offer a more effective treatment option for atrophic acne scars.
What could go wrong
This is a small, early-stage trial, so results may not apply to everyone. Chemical peels can cause irritation, burning, or changes in skin color, and the added benefit over microneedling alone is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Dec 2024

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults of either sex aged 18 years or older. * Presence of atrophic acne scars of any type or duration. * Fitzpatrick skin type I to IV. Exclusion Criteria: * Active inflammatory acne lesions, skin infection, or a tendency to develop keloids. * Immunocompromised state, facial cancer, or severely damaged facial skin. * Known hypersensitivity to glycolic acid or trichloroacetic acid. * Oral isotretinoin use within 6 months before enrollment. * Pregnancy or breastfeeding. * Inability or unwillingness to adhere to study procedures. * Unrealistic expectations regarding treatment outcomes.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne vulgaris Atrophic acne scars

Contacts and locations

Locations

  • Faculty of Medicine, Kafrelsheikh University

    Kafr ash Shaykh, Egypt

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