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Could a poop pill cure bald spots? new trial tests microbiota transplant for alopecia

NCT ID NCT06747611

Recruiting now Disease control Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether transplanting healthy gut bacteria can help people with alopecia areata, an autoimmune disease that causes patchy or total hair loss. Forty adults with moderate to severe hair loss will take either antibiotic and microbiota transplant capsules or a placebo for two weeks. Researchers will track hair regrowth and changes in gut and skin bacteria for up to 54 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Vancomycin, Neomycin, and microbiota transplant capsules
What this could lead to
If it works, this could point toward a new treatment for alopecia areata that targets gut bacteria instead of using immune-suppressing drugs.
What could go wrong
This is a small, early Phase 2 trial with only 40 people. It is testing whether the transplant can change gut bacteria, not yet whether it reliably regrows hair. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alopecia areata alopecia totalis alopecia universalis alopecia universalis congenita

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALOPECIA AREATA ALOPECIA TOTALIS ALOPECIA UNIVERSALIS

Contacts and locations

Locations

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

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