Gut bacteria swap could disarm superbugs in hospital patients

NCT ID NCT05835206

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a microbiome therapy—a capsule of healthy gut bacteria—can reduce drug-resistant bacteria living in the gut of hospitalized patients. About 40 adults who carry these superbugs will receive either the therapy or a placebo. The goal is to see if the treatment safely lowers the amount of resistant bacteria and helps prevent future infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
encapsulated intestinal microbiota (microbiome therapy)
What this could lead to
If successful, this could offer a way to reduce dangerous antibiotic-resistant bacteria in the gut, lowering infection risk and the need for strong antibiotics.
What could go wrong
This is a small early-phase trial with only 40 participants, so results may not apply broadly. The therapy may not effectively clear the bacteria or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory Johns Creek Hospital

    RECRUITING

    Johns Creek, Georgia, 30097, United States

  • Emory Rehabilitation Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Clinical Research Network

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Hospital (EUH)

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Hospital Midtown

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Emory University at Wesley Woods Hospital

    RECRUITING

    Atlanta, Georgia, 30329, United States