Yo-Yo diet breakthrough? antibiotics may stop weight regain

NCT ID NCT06681246

First seen Jan 23, 2026 · Last updated May 13, 2026 · Updated 16 times

Summary

This study explores whether changing gut bacteria with antibiotics can prevent weight regain after losing at least 10% of body weight. Researchers will give antibiotics or a placebo to 200 adults with obesity (BMI 28-35) and track weight and microbiome changes. The goal is to find a new way to stop the common cycle of losing and regaining weight.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Weizmann Institute of Science

    RECRUITING

    Rehovot, Israel

    Contact

Conditions

Explore the condition pages connected to this study.