Could a new toothpaste tame gum disease by keeping good bacteria happy?

NCT ID NCT07397312

Recruiting now Disease control Sponsor: Periotrap Pharmaceuticals GmbH Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests a new toothpaste designed to protect the natural balance of bacteria in the mouth. 28 adults with periodontitis will brush twice daily for 3 months while continuing their usual gum disease care. Researchers will check if the toothpaste improves oral health compared to before use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: microbiome-modulating toothpaste
What this could lead to: If it works, this could point toward a simple daily toothpaste that helps control gum disease by supporting a healthy mouth microbiome.
What could go wrong: This is a very small pilot study (28 people) with no blinding or placebo control, so results may not be reliable or generalizable. The toothpaste is a cosmetic product, not a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTITIS

Contacts and locations

Locations

Dr. G. Jungbauer
RECRUITING

Straubing, 94315, Germany
Dr. Hofmann
NOT_YET_RECRUITING

Bietigheim-Bissingen, 74321, Germany
Dr. T. Schütz
RECRUITING

Borna, 04552, Germany

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