New drug shows promise for kidney disease in early trial

NCT ID NCT05174221

First seen Jan 31, 2026 · Last updated May 12, 2026 · Updated 8 times

Summary

This early-stage study tested a drug called mezagitamab in 17 people with IgA nephropathy, a kidney disease. The main goal was to check for side effects and see how the body processes the drug. Participants received weekly injections for 8 weeks, then every two weeks for 16 weeks, and were monitored for up to 96 weeks.

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Contacts and locations

Locations

  • ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia

    Brescia, Lombardy, 25123, Italy

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Amicis Research Center - Northridge - Nordhoff

    Northridge, California, 91324, United States

  • Beijing Friendship Hospital,Capital Medical University

    Beijing, Beijing Municipality, 100050, China

  • Boise Kidney and Hypertension Institute - Frenova

    Nampa, Idaho, 83687, United States

  • Core Research Group

    Milton, Queensland, 4064, Australia

  • Fujita Health University Hospital

    Toyoake-shi, Aiti, 470-1192, Japan

  • Fundacio Puigvert

    Barcelona, 8025, Spain

  • Guangdong Provincial Peoples Hospital

    Guangzhou, Guangdong, 510080, China

  • Hiroshima University Hospital

    Hiroshima, Hiroshima, 734-8551, Japan

  • Hospital Universitario Marques de Valdecilla

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Vall d'Hebron - PPDS

    Barcelona, 08035, Spain

  • Hull Royal Infirmary

    Hull, HU3 2JZ, United Kingdom

  • Kasugai Municipal Hospital

    Kasugai-Shi, Aiti, 486-0804, Japan

  • Leicester General Hospital

    Leicester, Leicestershire, LE5 4PW, United Kingdom

  • Monash Health, Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

  • National University Hospital- Singapore

    Singapore, 119074, Singapore

  • NorthShore University HealthSystem

    Evanston, Illinois, 60201, United States

  • Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • Sapporo City General Hospital

    Sapporo, Hokkaido, 060-8604, Japan

  • Semmelweis Egyetem

    Budapest, 1083, Hungary

  • Seoul National University Hospital

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont

    Szeged, Csongrád megye, 6720, Hungary

  • Taipei Medical University Shuang Ho Hospital

    New Taipei City, 23561, Taiwan

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, 710061, China

Conditions

Explore the condition pages connected to this study.