New drug mevidalen aims to ease Alzheimer's symptoms in 300-Person trial

NCT ID NCT06538116

Completed Symptom relief Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug mevidalen can safely improve thinking, memory, and daily function in people with mild-to-moderate Alzheimer's disease. About 300 participants will receive either mevidalen or a placebo for 26 weeks. The main goal is to see if the drug eases symptoms like confusion and difficulty with everyday tasks.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE

Contacts and locations

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Locations

AMC Research, LLC dba Flourish Research

Matthews, North Carolina, 28105, United States
Accel Research Sites - NeuroStudies CRU

Decatur, Georgia, 30030, United States
ActivMed Practices & Research, LLC

Methuen, Massachusetts, 01844, United States
Akita City Hospital

Akita, 010-0933, Japan
Ascension Alexian Brothers

Elk Grove Village, Illinois, 60007, United States
Banner Alzheimer's Institute

Phoenix, Arizona, 85006, United States
Baptist Health Center for Clinical Research LLC

Little Rock, Arkansas, 72205, United States
Be Well Clinical Studies

Round Rock, Texas, 78681, United States
Brain Matters Research

Stuart, Florida, 34997, United States
California Neuroscience Research, LLC

Sherman Oaks, California, 91403, United States
Catalina Research Institute

Montclair, California, 91763, United States
Cedar Health Research, LLC

Euless, Texas, 76040, United States
CenExel Advanced Memory Research Institute of NJ

Toms River, New Jersey, 08755, United States
CenExel iResearch Atlanta

Decatur, Georgia, 30030, United States
CenExel iResearch, LLC

Savannah, Georgia, 31405, United States
Charter Research - The Villages

The Villages, Florida, 32162, United States
Charter Research, LLC

Orlando, Florida, 32803, United States
Clinical Neuroscience Solutions, Inc.

Jacksonville, Florida, 32256, United States
Clinical Neuroscience Solutions, Inc.Ta

Memphis, Tennessee, 38119, United States
Clinical Trial Network LLC

Houston, Texas, 77074, United States
Clinical Trials of Texas, LLC San Antonio dba Flourish Research

San Antonio, Texas, 78229, United States
Conquest Research

Winter Park, Florida, 32789, United States
El Faro Health and Therapeutics

Rio Grande City, Texas, 78582, United States
Excel Medical Clinical Trials, LLC Boca Raton dba Flourish Research

Boca Raton, Florida, 33434, United States
Eximia Clinical Research-NC, LLC

Raleigh, North Carolina, 27612, United States
Hawaii Pacific Neuroscience

Honolulu, Hawaii, 96817, United States
Himeji Central Hospital Clinic

Himeji-shi, 672-8043, Japan
Ikuseikai Shinozuka Hospital

Fujioka-shi, 375-0017, Japan
Inage Neurology and Memory Clinic

Chiba, 263-0043, Japan
Intercoastal Medical Group

Sarasota, Florida, 34239, United States
JEM Research Institute

Atlantis, Florida, 33462, United States
Josephson, Wallack, Munshower Neurology, P.C.

Indianapolis, Indiana, 46256, United States
Katayama Medical Clinic

Kurashiki-shi, 710-0813, Japan
Kerwin Medical Center

Dallas, Texas, 75231, United States
Keystone Clinical Studies, LLC Philadelphia dba Flourish Research

Plymouth Meeting, Pennsylvania, 19462, United States
Kishikai Kishi Hospital

Kiryu-shi, 376-0011, Japan
Koseikai Cocoro Hospital Kusatsu

Hiroshima, 733-0864, Japan
Kuramitsu Hospital

Fukuoka, 819-0037, Japan
Mabashi Clinic

Matsudo-shi, 271-0047, Japan
Memory Clinic Ochanomizu

Bunkyō City, 113-0034, Japan
Memory Clinic Toride

Toride-shi, 302-0004, Japan
Mental Clinic Sakurazaka

Fukuoka, 810-0023, Japan
Merritt Island Medical Research, LLC dba Flourish Research

Merritt Island, Florida, 32952, United States
NHO Hizen Psychiatric Medical Center

Kanzaki-gun, 842-0192, Japan
National Center for Geriatrics and Gerontology

Obu-shi, 474-8511, Japan
Neuropain Medical Center

Fresno, California, 93710, United States
Neuropsychiatric Research Center of Southwest Florida

Fort Myers, Florida, 33912, United States
Oita University Hospital

Yufu-shi, 879-5593, Japan
Premiere Research Institute at Palm Beach Neurology

West Palm Beach, Florida, 33407, United States
Profound Research LLC At The Neurology Center of Southern California

Carlsbad, California, 92011, United States
Progressive Medical Research

Port Orange, Florida, 32127, United States
QUEST Research Institute

Farmington Hills, Michigan, 48334, United States
Rainbow & Sea Hospital

Karatsu-shi, 847-0031, Japan
Renstar Medical Research

Ocala, Florida, 34470, United States
Senior Adults Specialty Research

Austin, Texas, 78757, United States
Southern TOHOKU Medical Clinic

Koriyama-shi, 963-8563, Japan
Suncoast Clinical Research - New Port Richey

New Port Richey, Florida, 34652, United States
Tokyo Medical University Hospital

Shinjuku-ku, 160-0023, Japan
Tokyo Metropolitan Bokutoh Hospital

Sumida-ku, 130-8575, Japan
University of Washington Medical Center

Seattle, Washington, 98104, United States
Vertex Clinical Research

Clermont, Florida, 34711, United States
Visionary Investigators Network

Aventura, Florida, 33180, United States
Visionary Investigators Network

Miami, Florida, 33176, United States
Yamagata University Hospital

Yamagata, 990-9585, Japan

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