Gum fluid protein may reveal hidden implant inflammation
NCT ID NCT07697729
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This study investigates whether a protein called Metrnl, found in the fluid around dental implants, could serve as a biological marker for peri-implantitis—a condition that causes inflammation and bone loss around implants. Researchers will compare Metrnl levels and other inflammatory markers in people with healthy implants versus those with peri-implantitis. The goal is to see if Metrnl can help distinguish between healthy and diseased implants, potentially leading to earlier and more accurate diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If Metrnl proves to be a reliable marker, it could lead to a simple, non-invasive test to detect peri-implantitis earlier and monitor treatment.
- What could go wrong
- This is a small observational study, not a treatment trial. The findings may not translate into a practical diagnostic tool, and Metrnl may not be specific enough to distinguish disease from health.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atatürk University
Erzurum, Erzurum, 25080, Turkey (Türkiye)
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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