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Cheap arthritis drug could tame severe eczema

NCT ID NCT00809172

Completed Disease control Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether methotrexate, an older drug used for arthritis, works as well as cyclosporine for people with moderate to severe atopic dermatitis (eczema). One hundred adults received either drug for 24 weeks. The main goal was to see if eczema severity dropped by half after 8 weeks. Researchers also tracked quality of life and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
methotrexate and cyclosporine
What this could lead to
If methotrexate works as well as cyclosporine, it could offer a safer long-term option for controlling severe eczema.
What could go wrong
This is a small, completed trial comparing two existing drugs. Neither is a cure, and both have side effects like kidney or liver risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

  • Hospices Civils de Lyon

    Lyon, France

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Other studies related to the condition(s) this trial covers.