Could one dose of methadone spare kids from extra pain meds after tonsil surgery?

NCT ID NCT06576830

Recruiting now Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a single dose of methadone (a long-acting opioid) given during surgery to standard short-acting opioids for pain relief after tonsillectomy in children ages 3 to 17. The goal is to see if methadone reduces the need for extra pain medication in the recovery room. About 440 children will take part, and the study is double-blind, meaning neither the patients nor the doctors know which treatment is given.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative sleep apnea syndrome tonsillitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN, POSTOPERATIVE PEDIATRIC SLEEP APNEA SLEEP DISORDERED BREATHING TONSILLAR HYPERTROPHY TONSILLITIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

Contact Email: •••••@•••••

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