Common diabetes pill tested to stop blood cancer before it starts

NCT ID NCT04850846

Summary

This study is testing whether metformin, a common diabetes medication, can prevent people with early blood cell conditions (MGUS and smoldering myeloma) from developing full multiple myeloma, a type of blood cancer. About 60 participants will take either metformin or a placebo pill daily for 6 months to see if the drug slows disease progression. The goal is to find a safe, preventive treatment for people at risk of developing cancer who currently have no approved therapies.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • DF/ BWCC in Clinical Affiliation with South Shore Hospital

    Weymouth, Massachusetts, 02190, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Dana-Farber at Brighton

    Brighton, Massachusetts, 02135, United States

  • Dana-Farber at Merrimack Valley

    Methuen, Massachusetts, 01844, United States

  • Dana-Farber at Milford

    Milford, Massachusetts, 01757, United States

  • Dana-Farber at NHOH

    Londonderry, New Hampshire, 35053, United States

Conditions

Explore the condition pages connected to this study.