Diabetes drug tested to fight TB and protect lungs in HIV patients

NCT ID NCT04930744

Summary

This study tested whether adding the common diabetes medication metformin to standard antibiotic treatment for tuberculosis (TB) is safe and helps people recover better, especially for those also living with HIV. Researchers wanted to see if metformin could help clear the TB infection faster and cause less lasting lung damage. About 112 adults with both TB and HIV were randomly assigned to receive either standard TB drugs alone or standard drugs plus metformin for 11 weeks.

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Contacts and locations

Locations

  • Isango Lethemba TB Research Unit

    Port Elizabeth, South Africa

  • Tembisa Clinical Research Centre-The Aurum Institute

    Johannesburg, Gauteng, 1632, South Africa

Conditions

Explore the condition pages connected to this study.