Could a common diabetes drug help fight a rare form of ALS?
NCT ID NCT04220021
First seen Dec 08, 2025 · Last updated May 11, 2026 · Updated 18 times
Summary
This study tests whether metformin, a common diabetes drug, is safe and tolerable for people with a specific genetic form of ALS (C9orf72 ALS). About 41 participants will take metformin for 24 weeks. The goal is to see if it can reduce harmful proteins in the body that are linked to the disease, potentially slowing its progression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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UF Health at the University of Florida
Gainesville, Florida, 32610, United States
Conditions
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