Could a diabetes drug and an antihistamine help repair MS damage?
NCT ID NCT05131828
First seen Jan 09, 2026 · Last updated May 07, 2026 · Updated 17 times
Summary
This study tested whether combining two common drugs—metformin (for diabetes) and clemastine (an antihistamine)—can help repair the protective coating around nerve cells in people with relapsing-remitting multiple sclerosis. 70 participants took the drug combination or a placebo for 24 weeks while continuing their usual MS treatment. The goal was to see if this approach could restore nerve function and potentially slow or reverse disability.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Addenbrooke's Hospital
Cambridge, United Kingdom
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