New combo therapy before surgery shows promise for rare skin cancer
NCT ID NCT05594290
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a short course of chemotherapy plus immunotherapy before surgery can improve outcomes for people with Merkel cell carcinoma, a rare skin cancer. About 36 adults with operable tumors will receive one cycle of retifanlimab and platinum-etoposide before their planned surgery. The main goal is to see how many patients have no cancer left in the removed tissue.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
Milan, 20133, Italy