Scientists dig deep into Mepolizumab's effects on nasal polyps and asthma

NCT ID NCT06069310

First seen Apr 19, 2026 · Last updated May 20, 2026 · Updated 5 times

Summary

This observational study follows 40 adults with chronic sinusitis with nasal polyps, with or without severe asthma, who are starting mepolizumab. Researchers collect nasal, blood, and sputum samples before treatment and at 3, 6, and 12 months to track changes in symptoms, gene activity, and airway bacteria. The goal is to find biological markers that predict who responds best to the drug, potentially reducing the need for steroids.

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Contacts and locations

Locations

  • Pulmonary Dept First ICU Evangelismos Hospital

    Athens, 10676, Greece

  • Pulmonary Dept First ICU, Evagelismos Hospital

    Athens, Attica, 10676, Greece

Conditions

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