New hope for kids with rare blood disorder: drug cuts flares and steroid use

NCT ID NCT04965636

First seen Jan 04, 2026 · Last updated May 17, 2026 · Updated 23 times

Summary

This study tested a drug called mepolizumab in 16 children aged 6 to 17 with hypereosinophilic syndrome (HES), a rare condition where too many white blood cells cause damage. The goal was to see if the drug could reduce disease flares and the need for steroids. Over 52 weeks, most children had fewer flares and could lower their steroid doses, suggesting mepolizumab helps control the disease but does not cure it.

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Contacts and locations

Locations

  • GSK Investigational Site

    Buenos Aires, C1028AAP, Argentina

Conditions

Explore the condition pages connected to this study.