Menthol vs. tobacco: which E-Cig helps smokers quit regular cigarettes?

NCT ID NCT05555069

Recruiting now Disease control Sponsor: Nikki Nollen, PhD, MA Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares menthol-flavored and tobacco-flavored e-cigarettes to see which helps adult menthol smokers switch from regular cigarettes. 800 participants who smoke at least 5 menthol cigarettes daily will use the assigned e-cigarette for 12 weeks. The main goal is to see how many completely switch to e-cigarettes by week 12.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Menthol-flavored electronic cigarette
What this could lead to: If successful, this could show that menthol-flavored e-cigarettes are a more effective tool to help menthol smokers switch away from combustible cigarettes.
What could go wrong: This is a behavioral study, not a treatment trial. Results may not apply to all smokers, and switching to e-cigarettes still carries health risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Smoking Reduction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING REDUCTION

Contacts and locations

Locations

University of Kansas Medical Center
RECRUITING

Kansas City, Missouri, 64130, United States

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