Memory retraining: a new hope for brain injury recovery?
NCT ID NCT04056312
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial tests whether a group-based memory training program, called the modified Story Memory Technique (mSMT), can improve memory and everyday functioning in people with traumatic brain injury (TBI). Participants attend twice-weekly sessions for five weeks, working on memory exercises via laptop in small groups. The study uses brain scans and memory tests to see if the training leads to lasting changes in brain function and real-world memory skills.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- group-based memory retraining exercises using the modified Story Memory Technique (mSMT)
- What this could lead to
- If effective, this group-based memory training could offer a practical, non-drug way to improve memory and quality of life for people with traumatic brain injury.
- What could go wrong
- This is a small, early-stage trial with only 45 participants, so results may not apply to everyone. The training requires multiple sessions and may not work for all types of memory problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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45 people
The number who actually took part.
- Started
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Jun 2016
- Finished
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Jun 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * I am between the ages of 18-65. * I have had a Traumatic Brain Injury at least one year ago. * I can read and speak English fluently. * I have difficulties with learning and memory skills. Exclusion Criteria: * I am currently taking steroids and /or benzodiazepines as determined by study staff review of my medications. * I have had a prior stroke or neurological injury/disease other than a traumatic brain injury. * I have a history of significant psychiatric illness (for example, bipolar disorder or psychosis) or a current diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II. * I have unstable or uncontrolled seizures. * I have a significant alcohol or drug abuse history.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kessler Foundation
West Orange, New Jersey, 07052, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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