New combo therapy aims to revive immune attack on hard-to-treat melanoma

NCT ID NCT05629546

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 29 times

Summary

This early-phase study tests a new treatment for advanced melanoma that has stopped responding to standard immunotherapy. It combines specially trained natural killer cells (either from the patient or a donor) with two immunotherapy drugs, nivolumab and relatlimab. The goal is to see if this combination is safe and can shrink tumors in 33 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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