Melatonin may ease Post-Surgery pain, cut narcotic use

NCT ID NCT04791943

First seen Feb 01, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study tested whether taking melatonin for three nights before wisdom tooth removal can lower pain and the need for painkillers after surgery. Sixty adults aged 18-35 took either melatonin or a placebo before their procedure. Researchers measured how many pain pills participants used and checked inflammatory markers in the blood.

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Contacts and locations

Locations

  • Montefiore Medical Center Department of Dentistry

    The Bronx, New York, 10467, United States

Conditions

Explore the condition pages connected to this study.