New vaccine combo aims to boost Body's fight against advanced skin cancer

NCT ID NCT04079166

Summary

This study is testing whether adding one of two experimental cancer vaccines (SCIB1 or iSCIB1+) to standard immunotherapy drugs can help people with advanced, inoperable melanoma. The goal is to see if the vaccines make the standard treatments work better and longer for patients. The trial will involve about 173 adults who have not had prior treatment for their advanced disease.

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Contacts and locations

Locations

  • Cambridge University Hospitals NHS Foundation Trust

    Cambridge, United Kingdom

  • East and North Hertfordshire NHS Trust

    Northwood, United Kingdom

  • Guy's & St Thomas' NHS Foundation Trust

    London, United Kingdom

  • Lancashire Teaching Hospitals NHS Foundation Trust

    Preston, United Kingdom

  • Nottingham University Hospitals NHS Trust

    Nottingham, United Kingdom

  • Oxford University Hospital NHS Foundation Trust

    Oxford, United Kingdom

  • Royal Free London NHS Foundation Trust

    London, United Kingdom

  • Sheffield Teaching Hospital NHS Foundation Trust

    Sheffield, United Kingdom

  • Somerset NHS Foundation Trust

    Taunton, United Kingdom

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • The Leeds Teaching Hospitals NHS Trust

    Leeds, United Kingdom

  • The Royal Marsden NHS Foundation Trust

    London, United Kingdom

  • University Hospital Plymouth NHS Trust

    Plymouth, United Kingdom

  • University Hospital Southampton NHS Foundation Trust

    Southampton, United Kingdom

  • Velindre University NHS Trust

    Cardiff, United Kingdom

Conditions

Explore the condition pages connected to this study.