New cocktail aims to tame Immunotherapy's worst side effects in melanoma
NCT ID NCT03999749
First seen Mar 28, 2026 · Last updated May 14, 2026 · Updated 4 times
Summary
This study tests whether adding the drug tocilizumab to the standard immunotherapy combination of ipilimumab and nivolumab can reduce serious immune-related side effects in people with advanced melanoma that cannot be removed by surgery. About 71 participants will receive the three drugs together for 12 weeks, followed by maintenance nivolumab alone for up to a year. The goal is to see if this approach makes the treatment safer while still controlling the cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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NYU Langone Health
New York, New York, 10016, United States
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The Angeles Clinic
Los Angeles, California, 90025, United States
Conditions
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