Major trial questions need for second surgery in melanoma patients

NCT ID NCT07530887

First seen Apr 28, 2026 · Last updated May 06, 2026 · Updated 1 time

Summary

This study tests whether people with melanoma can safely avoid a second surgery (re-excision) after the initial tumor is removed. About 1,749 adults with early to advanced melanoma but no spread will be randomly assigned to get standard re-excision or no further surgery. Researchers will track cancer return, survival, side effects, and quality of life to see if skipping re-excision is safe and beneficial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alrijne Ziekenhuis

    NOT_YET_RECRUITING

    Leiden, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Antoni van Leeuwenhoek

    RECRUITING

    Amsterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Catharina ziekenhuis

    NOT_YET_RECRUITING

    Eindhoven, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Diakonessenhuis

    RECRUITING

    Utrecht, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dijklander Ziekenhuis

    NOT_YET_RECRUITING

    Hoorn, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Flevoziekenhuis

    RECRUITING

    Almere Stad, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gelre ziekenhuizen

    RECRUITING

    Apeldoorn, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Groene Hart Ziekenhuis

    NOT_YET_RECRUITING

    Gouda, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Haaglanden Medisch Centrum

    RECRUITING

    The Hague, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Haga Ziekenhuis

    NOT_YET_RECRUITING

    The Hague, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Isala Ziekenhuis

    NOT_YET_RECRUITING

    Zwolle, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jeroen Bosch Ziekenhuis

    RECRUITING

    's-Hertogenbosch, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Leids Universitair Medisch Centrum

    RECRUITING

    Leiden, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maasstad Ziekenhuis

    NOT_YET_RECRUITING

    Rotterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maastricht UMC

    NOT_YET_RECRUITING

    Maastricht, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Martini ziekenhuis

    NOT_YET_RECRUITING

    Groningen, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medisch Spectrum Twente

    RECRUITING

    Enschede, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Noordwest Ziekenhuisgroep

    RECRUITING

    Alkmaar, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rijnstate Ziekenhuis

    RECRUITING

    Arnhem, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Antonius Ziekenhuis

    NOT_YET_RECRUITING

    Utrecht, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tergooi MC

    NOT_YET_RECRUITING

    Hilversum, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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