Scientists probe why some melanoma patients respond to immunotherapy

NCT ID NCT02626065

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at 32 people with advanced melanoma who were treated with the immunotherapy drug Nivolumab. Researchers took blood samples before and during treatment to track changes in immune cells. The goal was to find differences between patients whose tumors shrank or stayed stable and those whose cancer kept growing, which could lead to better treatment strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Nivolumab
What this could lead to
If successful, this could help doctors predict which melanoma patients will benefit from Nivolumab and improve treatment strategies.
What could go wrong
This is a small, completed study focused on understanding immune responses, not testing a new treatment. Results may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69310, France

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