New skin cancer drug combo faces off against approved treatment in major trial

NCT ID NCT06246916

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new combination of two immunotherapy drugs (fianlimab and cemiplimab) works better than an already approved combination (Opdualag) for treating advanced melanoma that cannot be removed by surgery. It will involve 560 adults with this type of skin cancer who have not yet received other drug treatments for their advanced disease. The main goal is to see if the new combination shrinks tumors more effectively and is safe for patients.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advocate Lutheran General Hospital
RECRUITING

Park Ridge, Illinois, 60068, United States
Allina Health Cancer Institute
RECRUITING

Minneapolis, Minnesota, 55407, United States
Arizona Oncology Associates
WITHDRAWN

Tucson, Arizona, 85711, United States
Banner MD Anderson Cancer Center
RECRUITING

Gilbert, Arizona, 85234, United States
Beacon Clinic
RECRUITING

Coeur d'Alene, Idaho, 83815, United States
Boca Raton Clinical Research (BRCR) Global
RECRUITING

Tamarac, Florida, 33321, United States
Cancer Specialist of North Florida
RECRUITING

Jacksonville, Florida, 32256, United States
Cancer and Blood Specialty Clinic
RECRUITING

Los Alamitos, California, 90720, United States
Center For Disease And Blood Disorder
RECRUITING

Fort Worth, Texas, 76104, United States
Centre Hospitalier Universitaire de Quebec (CHUQ) - Centre Hospitalier de l'Universite Laval (CHUL)
RECRUITING

Québec, G1J 0J9, Canada
Clermont Oncology Center
RECRUITING

Clermont, Florida, 34711, United States
Comprehensive Cancer Centers of Nevada
RECRUITING

Las Vegas, Nevada, 89148, United States
Dartmouth Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Duke Health System
RECRUITING

Durham, North Carolina, 27710, United States
Eisenhower Medical Center
RECRUITING

Rancho Mirage, California, 92270, United States
Emad Ibrahim, MD, Inc.
RECRUITING

Redlands, California, 92373, United States
Fort Wayne Medical Oncology and Hematology
RECRUITING

Fort Wayne, Indiana, 46825, United States
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States
H. Lee Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Henry Ford Cancer Institute/Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
Hope and Healing Cancer Services
RECRUITING

Hinsdale, Illinois, 60521, United States
Illinois CancerCare
RECRUITING

Peoria, Illinois, 61615, United States
Inova Schar Cancer Institute
RECRUITING

Fairfax, Virginia, 22031, United States
Ironwood Cancer & Research Centers
RECRUITING

Chandler, Arizona, 85224, United States
Jewish General Hospital - Main Address
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Joe Arrington Cancer Research & Treatment Center
RECRUITING

Lubbock, Texas, 79410, United States
John B. Amos Cancer Center
WITHDRAWN

Columbus, Georgia, 31904, United States
John Theurer Cancer Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Kadlec Clinic Hematology and Oncology
RECRUITING

Kennewick, Washington, 99336, United States
Kaiser Foundation Hospitals
RECRUITING

Portland, Oregon, 97227, United States
Karmanos Cancer Institute
RECRUITING

Detroit, Michigan, 48201, United States
Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28204, United States
Lifespan Cancer Institute
RECRUITING

Providence, Rhode Island, 02903, United States
London Regional Cancer Centre
RECRUITING

London, Ontario, N6A 5W9, Canada
Markey Cancer Center Clinical Research Organization
RECRUITING

Lexington, Kentucky, 40536, United States
Mary Bird Perkins Cancer Center
RECRUITING

Baton Rouge, Louisiana, 70809, United States
Maryland Oncology Hematology, P.A.
RECRUITING

Columbia, Maryland, 21044, United States
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Mercy South
RECRUITING

St Louis, Missouri, 63128, United States
Messino Cancer Center
RECRUITING

Asheville, North Carolina, 28806, United States
Minnesota Oncology Hematology, P.A
RECRUITING

Fridley, Minnesota, 55432, United States
New York Oncology Hematology
RECRUITING

Albany, New York, 12206, United States
Novant Health Cancer Institute
RECRUITING

Charlotte, North Carolina, 28204, United States
Novant Health Weisiger Cancer Institute - Charlotte
RECRUITING

Charlotte, North Carolina, 28204, United States
Novant Health Zimmer Cancer Institute - Wilmington
RECRUITING

Wilmington, North Carolina, 28401, United States
Oklahoma Cancer Specialists and Research Institute, LLC
RECRUITING

Tulsa, Oklahoma, 74146, United States
Oncology & Hematology Associates of Southwest Virginia, Inc.
RECRUITING

Roanoke, Virginia, 24014, United States
Oncology Associates of Oregon PC
RECRUITING

Eugene, Oregon, 97401, United States
Oncology Hematology Care Clinical Trials
RECRUITING

Cincinnati, Ohio, 45242, United States
Oncology Hematology West P.C. dba Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130, United States
Oregon Health and Science University
RECRUITING

Portland, Oregon, 97239, United States
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Providence Medical Foundation
RECRUITING

Fullerton, California, 92835, United States
Rocky Mountain Regional VA Medical Center
RECRUITING

Aurora, Colorado, 80045, United States
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08901, United States
Saint Francis Cancer Center
RECRUITING

Greenville, South Carolina, 29607, United States
Sansum Clinic
RECRUITING

Santa Barbara, California, 93105, United States
Sarah Cannon Research Institute (SCRI) Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States
Seidman Cancer Center
RECRUITING

Cleveland, Ohio, 44106, United States
St John's Cancer Institute
RECRUITING

Santa Monica, California, 90404, United States
St. Joseph Hospital Orange
RECRUITING

Orange, California, 92868, United States
St. Luke's University Health Network
RECRUITING

Easton, Pennsylvania, 18045, United States
St. Vincent Healthcare
RECRUITING

Billings, Montana, 59102, United States
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
Sutter Health
RECRUITING

Sacramento, California, 95816, United States
Swedish Cancer Institute
RECRUITING

Seattle, Washington, 98104, United States
Swedish Cancer Institute - Edmonds Campus
RECRUITING

Edmonds, Washington, 98026, United States
Swedish Cancer Institute - Issaquah Campus
RECRUITING

Issaquah, Washington, 98029, United States
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States
Tennessee Oncology - Chattanooga
RECRUITING

Chattanooga, Tennessee, 37404, United States
Texas Oncology
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology - Austin Central, Central Austin Cancer Center
RECRUITING

Austin, Texas, 78731, United States
Texas Oncology - Austin Midtown, Midtown Medical Center I
RECRUITING

Austin, Texas, 78705, United States
Texas Oncology - Bedford
RECRUITING

Bedford, Texas, 76022, United States
Texas Oncology - Fort Worth
RECRUITING

Fort Worth, Texas, 76104, United States
Texas Oncology - Grapevine
RECRUITING

Grapevine, Texas, 76051, United States
Texas Oncology - Harlingen, Medical Arts Pavillion
RECRUITING

Harlingen, Texas, 78550, United States
Texas Oncology - Longview
RECRUITING

Longview, Texas, 75601, United States
Texas Oncology - McAllen
RECRUITING

McAllen, Texas, 78503, United States
Texas Oncology - Medical City
RECRUITING

Dallas, Texas, 75230, United States
Texas Oncology - Weslaco, Knapp Medical Plaza
RECRUITING

Weslaco, Texas, 78596, United States
Texas Oncology-Palestine Cancer Center
RECRUITING

Palestine, Texas, 75801, United States
Texas Oncology-Tyler, Northeast Texas Cancer Institute
RECRUITING

Tyler, Texas, 75702, United States
The Melanoma And Skin Cancer Institute
RECRUITING

Englewood, Colorado, 80113, United States
The Ohio State University Wexner Medical Center
RECRUITING

Columbus, Ohio, 43210, United States
The University of Kansas Cancer Center
RECRUITING

Westwood, Kansas, 66205, United States
The University of Texas Health Science Center at Tyler D/B/A UT Health East Texas HOPE Cancer Center
WITHDRAWN

Tyler, Texas, 75701, United States
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
The Valley Hospital Inc.
RECRUITING

Paramus, New Jersey, 07652, United States
UCHealth
RECRUITING

Fort Collins, Colorado, 80528, United States
University Cancer & Blood Center
RECRUITING

Athens, Georgia, 30607, United States
University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States
University of California Los Angeles
RECRUITING

Los Angeles, California, 90024, United States
University of California San Francisco (UCSF)
RECRUITING

San Francisco, California, 94143, United States
University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
University of Tennessee Medical Center
RECRUITING

Knoxville, Tennessee, 37920, United States
University of Utah Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 84112, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22908, United States
University of Wisconsin Carbone Cancer Center
RECRUITING

Madison, Wisconsin, 53792, United States
VA St. Louis Healthcare System
RECRUITING

St Louis, Missouri, 63106, United States
Virginia Cancer Specialists, PC
RECRUITING

Fairfax, Virginia, 22031, United States
Virginia Commonwealth University Massey Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States
Washington University
RECRUITING

St Louis, Missouri, 63110, United States
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States
Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

MELANOMA