New drug combo tested before brain surgery for melanoma patients

NCT ID NCT05704933

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 22 times

Summary

This early study tested whether giving a single dose of immune-boosting drugs (nivolumab with either ipilimumab or relatlimab) before brain surgery is safe and possible for people with melanoma that has spread to the brain. Only one person took part, so the main goal was to see if the approach could work and to study how immune cells change. The study did not aim to cure or control the disease directly, but to gather information for future research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M.D. Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.