Can targeted exercises unpinch nerves and ease thoracic outlet syndrome?

NCT ID NCT07785427

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time

Summary

This trial tests whether a specific physical therapy approach—mechanically loaded neuro-dynamics—can ease symptoms of thoracic outlet syndrome, a condition where nerves or blood vessels get compressed near the collarbone. About 36 adults with the condition will follow an 11-week exercise program using resistance bands, with intensity gradually increasing. Researchers will measure changes in pain, neck and shoulder range of motion, nerve function, and quality of life to see if this therapy helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mechanically loaded neuro-dynamics, a physical therapy exercise protocol using resistance bands
What this could lead to
If effective, this exercise approach could offer a non-surgical way to reduce pain, improve shoulder and neck movement, and boost quality of life for people with thoracic outlet syndrome.
What could go wrong
This is a small, early-stage trial, so results may not apply broadly. The exercises involve progressive loading, which could temporarily increase symptoms if not carefully monitored.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 36 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

24 to 37 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Subjects from both genders diagnosed with Thoracic Outlet Syndrome will be recruited through direct referrals from their neurosurgeon. 2. Subjects age between 30.8±7.4 years 3. Subjects body mass index = 19.5±2.8 4. Control group includes health volunteer subjects with negative root test results under supervision of neurosurgeon. Exclusion Criteria: The exclusion criteria are: 1. head injury, stroke. 2. epilepsy episodes. 3. mental disorders. 4. cardiovascular disease. 5. having a pacemaker or cochlear implant. 6. pregnancy, oncological episodes, inflammatory disease, myelopathy, degenerative changes in the cervical spine (after verification on computed tomography or magnetic resonance imaging scans). 7. peripheral neuropathies from the level of the arm and COVID-19-related symptoms

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • out-patient clinic, faculty of physical therapy - Kafrelsheikh University.

    Kafr ash Shaykh, Egypt

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