New hope for debilitating fatigue? trial tests drug combo for ME/CFS and long COVID

NCT ID NCT06366724

Summary

This study is testing whether two existing medications, pyridostigmine and low-dose naltrexone, can help improve symptoms and function for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID. It will involve 160 adults who have these conditions with a specific problem called orthostatic intolerance. Participants will be randomly assigned to receive one of the drugs, both, or a placebo for about three months to see if the treatments help with energy, exercise capacity, and daily symptoms.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.