New spine cage aims to improve back surgery outcomes

NCT ID NCT07414745

Recruiting now Disease control Sponsor: Medtronic Spinal and Biologics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study compares a new spine cage device (MDT-0123) to a standard bone graft for patients needing two-level spinal fusion in the lower back. About 140 adults with disc degeneration or spinal deformity will be enrolled in Japan. The main goal is to see if the device leads to better bone fusion and fewer side effects after 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MDT-0123 spine cage and kit
What this could lead to: If successful, this device could offer a safer or more effective alternative to traditional bone graft for spinal fusion surgery.
What could go wrong: This is an early-stage trial with only 140 participants in Japan. The device may not prove superior to the standard bone graft, and risks include device-related side effects or failed fusion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISC DEGENERATION SPINAL DEFORMITY

Contacts and locations

Locations

Dokkyo Medical University Saitama Medical Center
NOT_YET_RECRUITING

Koshigaya, Saitama, 343-8555, Japan
Japan Community Health care Organization Osaka Hospital
RECRUITING

Osaka, 553-0003, Japan
Keio University Hospital
NOT_YET_RECRUITING

Shinjuku-Ku, Tokyo, 160-8582, Japan
Kitano Medical Research Institute Hospital
RECRUITING

Osaka, 530-8480, Japan
Kobe University Hospital
RECRUITING

Kobe, Hyōgo, 650-0017, Japan
Kyoto City Hospital
RECRUITING

Kyoto, 604-8845, Japan
Osaka General Hospital of West Japan Railway Company
NOT_YET_RECRUITING

Osaka, 545-0053, Japan
Seirei Hamamatsu General Hospital
NOT_YET_RECRUITING

Hamamatsu, Shizuoka, 430-8558, Japan
Shunyokai Medical Corporation Sangubashi Spine Surgery Hospital
NOT_YET_RECRUITING

Shibuya-Ku, Tokyo, 151-0053, Japan
Sonoda Medical Corporations Sonoda Third Hospital
RECRUITING

Adachi-Ku, Tokyo, 121-0807, Japan
Tokai University Hospital
NOT_YET_RECRUITING

Isehara, Kanagawa, 259-1193, Japan
Tokyo General Hospital
NOT_YET_RECRUITING

Nakano-Ku, Tokyo, 165-0022, Japan
Toranomon Hospital
NOT_YET_RECRUITING

Minato-Ku, Tokyo, 105-8470, Japan
Wakakusa Daiichi Hospital
NOT_YET_RECRUITING

Higashiosaka, Osaka, 579-8056, Japan

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