New MRI-Guided radiation aims to spare cancer patients from chronic dry mouth

NCT ID NCT03972072

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of radiotherapy that uses daily MRI scans to precisely target head and neck cancer while avoiding the saliva glands. The goal is to reduce severe dry mouth, a common and lasting side effect. Forty-nine patients will receive this adaptive treatment and be followed for two years to measure saliva flow and dry mouth severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI-guided adaptive radiotherapy

What this could lead to

If it works, this approach could significantly reduce chronic dry mouth in head and neck cancer survivors, improving their quality of life.

What could go wrong

This is a small, early-phase study with only 49 participants, so results may not apply to everyone. The technique is complex and may not be widely available.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Zurich University Hospital

    Zurich, 8091, Switzerland