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Could a weekly shot replace your sleep apnea machine?

NCT ID NCT07226765

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Nov 11, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests a new drug, maridebart cafraglutide, for adults with obstructive sleep apnea who are overweight or obese and not using a breathing machine (PAP therapy). Over 52 weeks, researchers will measure if the drug reduces breathing pauses during sleep and helps with weight loss. The goal is to see if this medication can control sleep apnea symptoms without needing a machine.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced Sleep Research

    RECRUITING

    Berlin, 10117, Germany

  • Aggarwal and Associates Ltd

    RECRUITING

    Brampton, Ontario, L6T 0G1, Canada

  • Basil Clinical

    RECRUITING

    Laurelton, New York, 11413, United States

  • CPQuali Pesquisa Clinica Ltda

    RECRUITING

    São Paulo, São Paulo, 01228-000, Brazil

  • CTI Clinical Research Center

    RECRUITING

    Cincinnati, Ohio, 45212, United States

  • CaRe Clinic

    RECRUITING

    Calgary, Alberta, T2N 4L7, Canada

  • Centro Medico Teknon

    RECRUITING

    Barcelona, Catalonia, 08022, Spain

  • Cerebrovaskularni poradna sro

    RECRUITING

    Ostrava - Poruba, 708 00, Czechia

  • Clinical Research Center Of Florida

    RECRUITING

    Pompano Beach, Florida, 33060, United States

  • Destiny Research Center

    RECRUITING

    Palmetto Bay, Florida, 33157, United States

  • Diabeteszentrum Hamburg West

    RECRUITING

    Hamburg, 22607, Germany

  • Epic Medical Research - DeSoto

    RECRUITING

    DeSoto, Texas, 75115, United States

  • Fakultni nemocnice Brno

    RECRUITING

    Brno, 625 00, Czechia

  • Fukuoka University Hospital

    RECRUITING

    Fukuoka, Fukuoka, 814-0180, Japan

  • FutureSearch Trials of Neurology

    RECRUITING

    Austin, Texas, 78731, United States

  • Gokeikai Osaka Kaisei Hospital

    RECRUITING

    Osaka, Osaka, 532-0003, Japan

  • Goodsleep Clinic

    RECRUITING

    Minato-ku, Tokyo, 105-0012, Japan

  • Hospital Medico Quirurgico San Rafael

    RECRUITING

    A Coruña, Galicia, 15006, Spain

  • Hospital Universitari Vall d Hebron

    RECRUITING

    Barcelona, Catalonia, 08035, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo Hcfmusp

    RECRUITING

    São Paulo, São Paulo, 05403-900, Brazil

  • InnoDiab Forschung

    RECRUITING

    Essen, 45136, Germany

  • Kuwamizu Hospital

    RECRUITING

    Kumamoto, Kumamoto, 862-0954, Japan

  • Monash Medical Centre

    RECRUITING

    Clayton, Victoria, 3168, Australia

  • Monroe Biomedical Research

    RECRUITING

    Monroe, North Carolina, 28112, United States

  • Nakamura Clinic

    RECRUITING

    Urasoe-shi, Okinawa, 901-2132, Japan

  • Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy

    RECRUITING

    Warsaw, 04-635, Poland

  • Nemocnice Rudolfa a Stefanie Benesov as

    RECRUITING

    Benesov U Prahy, 256 01, Czechia

  • NeuroTrials Research

    RECRUITING

    Atlanta, Georgia, 30328, United States

  • Northwest Clinical Research Center

    RECRUITING

    Bellevue, Washington, 98007, United States

  • Nucleo de Pesquisa do Rio Grande do Sul

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90430-001, Brazil

  • Peninsula Research Associates

    RECRUITING

    Rolling Hills Estates, California, 90274, United States

  • RESM ShinYokohama Sleep and Respiratory Medical Care Clinic

    RECRUITING

    Yokohama, Kanagawa, 222-0033, Japan

  • Red-Institut GmbH

    RECRUITING

    Oldenburg, 23758, Germany

  • Reformatus Pulmonologiai Centrum

    RECRUITING

    Törökbálint, 2045, Hungary

  • Royal Brisbane and Womens Hospital

    RECRUITING

    Herston, Queensland, 4006, Australia

  • Saiseikai Futsukaichi Hospital

    RECRUITING

    Chikushino-shi, Fukuoka, 818-8516, Japan

  • Siteworks - Zentrum fuer klinische Studien Hannover

    RECRUITING

    Hanover, 30449, Germany

  • Siteworks - Zentrum fuer klinische Studien Karlsruhe

    RECRUITING

    Karlsruhe, 76137, Germany

  • Sleep Therapy & Research Center

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Sleep and Mental Clinic-Kitahiroshima

    RECRUITING

    Kitahiroshima-shi, Hokkaido, 061-1121, Japan

  • SomnoCenter Budapest Alvaszavar Kozpont

    RECRUITING

    Budapest, 1012, Hungary

  • Teradan Clinical Trials

    RECRUITING

    Brandon, Florida, 33511, United States

  • Valley Clinical Trials

    RECRUITING

    Northridge, California, 91325, United States

  • Wharton Medical Clinic

    RECRUITING

    Hamilton, Ontario, L8L 5G8, Canada

  • Woolcock Institute of Medical Research

    RECRUITING

    Macquarie Park, New South Wales, 2113, Australia

Conditions

Explore the condition pages connected to this study.

OBSTRUCTIVE SLEEP APNEA