Jaw surgery antibiotics under scrutiny: MANTRA trial seeks answers

NCT ID NCT05964140

First seen Jan 27, 2026 · Last updated Jun 18, 2026 · Updated 24 times

Summary

This study looks at whether antibiotics are needed after surgery for a broken jaw. Many doctors prescribe them to prevent infection, but overuse can lead to antibiotic resistance. The trial will compare three approaches: no antibiotics after surgery, a short course, or a longer course, to see which works best for preventing infection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • East Lancashire Hospitals NHS Trust

    RECRUITING

    Blackburn, Lancashire, BB2 3HH, United Kingdom

  • East Lancashire Hospitals NHS Trust

    NOT_YET_RECRUITING

    Blackburn, Lancashire, BB2 3HH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

jaw fracture Mandibular Fractures Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.