Jaw surgery antibiotics under scrutiny: MANTRA trial seeks answers

NCT ID NCT05964140

Recruiting now Disease control Sponsor: East Lancashire Hospitals NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether antibiotics are needed after surgery for a broken jaw. Many doctors prescribe them to prevent infection, but overuse can lead to antibiotic resistance. The trial will compare three approaches: no antibiotics after surgery, a short course, or a longer course, to see which works best for preventing infection.

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Conditions

The condition(s) this trial relates to.

jaw fracture Mandibular Fractures Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MANDIBLE FRACTURE POST-OPERATIVE ANTIBIOTICS

Contacts and locations

Locations

East Lancashire Hospitals NHS Trust
RECRUITING

Blackburn, Lancashire, BB2 3HH, United Kingdom
East Lancashire Hospitals NHS Trust
NOT_YET_RECRUITING

Blackburn, Lancashire, BB2 3HH, United Kingdom

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