Could a simple sugar alcohol prevent delirium after a heart attack?

NCT ID NCT06759259

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving mannitol, a substance that reduces brain swelling, could prevent delirium in older adults hospitalized for a heart attack. Fifty patients aged 65 and older with high inflammation levels were included. The goal was to see if mannitol could lower the chance of developing confusion and other delirium symptoms during their hospital stay.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mannitol
What this could lead to
If it works, this could point toward a simple, low-cost way to prevent delirium in older heart attack patients.
What could go wrong
This is a very small, single-center study with only 50 participants. Results may not apply to all patients, and the effect may be modest or absent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardiology Reserch Institute Tomsk National Research Centre

    Tomsk, Tomsk Oblast, 634012, Russia

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