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Can mango timing tame blood sugar spikes?

NCT ID NCT06986161

Disease control Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 28, 2026 · Last updated Aug 28, 2026

Summary

Researchers are testing whether having mango before or after a meal changes how the body handles blood sugar and inflammation in people with prediabetes. The study involves 33 adults aged 20 to 60 who are overweight and have elevated fasting glucose or HbA1c. Participants will consume a mango beverage or a control drink at different times relative to a meal, and researchers will measure glucose, insulin, and inflammatory markers. The goal is to see if mango's natural compounds can improve metabolic responses and how they are absorbed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mango beverage
What this could lead to
If timing mango intake around meals improves blood sugar control, it could offer a simple dietary strategy to help manage prediabetes and reduce diabetes risk.
What could go wrong
This is a small early-stage trial, so results may not apply broadly. Mango contains natural sugars, which could offset any benefits, and the effect on long-term diabetes prevention remains uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

33 people

The number who actually took part.

Started

Apr 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be between 20-60 years old. * Have a BMI of 25-35 kilograms per square meter. * Have fasting blood glucose between 100-125 milligrams per deciliter or Glycated hemoglobin (HbA1c) between 5.7-6.4%. * Be non-smokers for at least 12 months. * Be generally healthy, with no major organ-related diseases. * Not take medications or supplements that could interfere with the study. * Be able to follow study procedures, including dietary restrictions and scheduled visits. Exclusion Criteria: * Smoke, vape, or use marijuana. * Have allergies or intolerance to mangoes or study foods. * Have blood pressure above 160/100 millimeters of Mercury. * Have fasting blood glucose above 125 milligrams per deciliter. * Have a history of major heart disease, stroke, or cancer in the past five years. * Be pregnant, planning to become pregnant, or breastfeeding. * Take anti-inflammatory drugs or certain dietary supplements. * Have had major surgery or trauma in the past two months. * Follow extreme diets (e.g., vegan, Atkins). * Have used antibiotics in the last six weeks. * Have a history of eating disorders or substance abuse in the past two years. * Drink more than three cups of coffee or tea per day. * Have donated blood in the last three months. * Be professional athletes or do excessive exercise. * Have had weight changes of more than 11 pounds in the past two months. * Work overnight shifts.

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Conditions

The condition(s) this trial relates to.

glucose intolerance prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pre diabetes

Contacts and locations

Locations

  • Clinical Nutrition Research Center

    Chicago, Illinois, 60616, United States

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