Can mindfulness ease joint pain from breast cancer treatment?

NCT ID NCT06728579

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two group therapy programs—Mindfulness Oriented Recovery Enhancement (MORE) and Supportive Psychotherapy—to help breast cancer survivors manage joint pain caused by aromatase inhibitors. About 200 women will attend weekly two-hour sessions for eight weeks and fill out questionnaires about pain, fatigue, anxiety, and quality of life. The goal is to see if these therapies can reduce pain and help women continue their medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mindfulness Oriented Recovery Enhancement (MORE) and Supportive Psychotherapy (SG) - both are behavioral group therapy programs
What this could lead to
If successful, this could offer breast cancer survivors a non-drug way to reduce joint pain and stay on their prescribed hormone therapy.
What could go wrong
This is a Phase 2 trial with 200 participants, so results are still preliminary. The therapies may not work for everyone, and benefits may vary.

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Conditions

The condition(s) this trial relates to.

Arthralgia breast cancer Cancer Pain Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Florida State University

    NOT_YET_RECRUITING

    Tallahassee, Florida, 32306, United States

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All Protocol Activities)

    RECRUITING

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

  • University of California San Diego (Data collection and Data analysis)

    RECRUITING

    San Diego, California, 92103, United States

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